FDPS antibody

Catalog No. ABIN5699809

This Rabbit Polyclonal antibody specifically detects FDPS in WB, ELISA and IP. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for FDPS antibody (ABIN5699809)

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FDPS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-FDPS Antibody

Purpose: FDPS antibody

Immunogen: farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FDPS

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Alternative Name: FDPS

Background:

Synonyms: Farnesyl pyrophosphate synthase (FPP synthase, FPS)|(2E,6E)-farnesyl diphosphate synthase|Dimethylallyltranstransferase|Farnesyl diphosphate synthase|Geranyltranstransferase|FDPS|FPS|KIAA1293

Background: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 39-41 kDa

Gene ID: 2224

UniProt: P14324

Pathways: Regulation of Muscle Cell Differentiation